Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06510-2715, USA.
J Glaucoma. 2012 Dec;21(9):590-5. doi: 10.1097/IJG.0b013e318220db03.
To examine whether automated visual field (VF) testing may exert a short-term influence on subsequent intraocular pressure (IOP) measurement during the same visit.
We reviewed patients with primary open-angle glaucoma whose most recent visit occurred at a major academic institution from July to December 2009 and who had 3 visits without intervening changes in glaucoma management within the previous 5 years. Exclusion criteria were patient admittance of nonadherence with medical therapy and documented difficulty of IOP measurement. One hundred nine right eyes from 109 patients were included. IOP obtained within 30 minutes after VF testing was compared with IOP from the previous and next visits without VF testing. Subgroup analyses included the role of reliability of VF test performance, surgical versus medical IOP control, and different topical medications.
The average IOP measured after VF testing was 14.9 ± 4.7 mm Hg, higher than both the previous (13.7 ± 4.4 mm Hg, P < 0.001) and next visits without VF examination (13.8 ± 4.4 mm Hg, P < 0.001). A total of 22.9% of patients experienced a more than 20% increase of IOP. Eyes with surgical control had less IOP elevation than eyes with medical control (3.1% ± 15.9% vs. 11.7% ± 17.4%, P = 0.009). Users of β-blockers or α-2-agonists had less IOP elevation than eyes controlled with prostaglandins or carbonic anhydrase inhibitors (0.9% ± 15.1% vs. 9.0% ± 12.3%, P = 0.030).
This retrospective study suggests that patients with primary open-angle glaucoma experience a small and transient increase in IOP after VF testing and that this effect may be lower after surgical pressure control.
研究自动视野（VF）检查是否会对同一次就诊时随后的眼压（IOP）测量产生短期影响。
我们回顾了 2009 年 7 月至 12 月在一家主要学术机构就诊的原发性开角型青光眼患者的资料，这些患者最近一次就诊时最近 5 年内没有改变青光眼治疗方案，并且在这 3 次就诊中没有进行过 IOP 测量。排除标准为患者不遵医嘱和记录的 IOP 测量困难。共纳入 109 例患者的 109 只右眼。比较了 VF 检查后 30 分钟内获得的 IOP 与无 VF 检查的前一次和下一次就诊的 IOP。亚组分析包括 VF 测试结果的可靠性、手术与药物控制眼压以及不同局部药物的作用。
VF 检查后测量的平均眼压为 14.9 ± 4.7mmHg，高于前一次（13.7 ± 4.4mmHg，P < 0.001）和无 VF 检查的下一次（13.8 ± 4.4mmHg，P < 0.001）。共有 22.9%的患者眼压升高超过 20%。手术控制眼压的眼比药物控制眼压的眼眼压升高幅度小（3.1%±15.9%比 11.7%±17.4%，P = 0.009）。使用β-阻滞剂或α-2-激动剂的眼眼压升高幅度小于使用前列腺素或碳酸酐酶抑制剂的眼（0.9%±15.1%比 9.0%±12.3%，P = 0.030）。
这项回顾性研究表明，原发性开角型青光眼患者在 VF 检查后眼压会出现小而短暂的升高，而手术控制眼压后这种效应可能较低。
