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[用纯化的牛白血病病毒制剂在犊牛中实验性诱导淋巴细胞白血病]

[Experimental induction of lympholeukemia in calves by a purified preparation of bovine leukemia virus].

作者信息

Kukaĭn R A, Nagaeva L I, Chapenko S V, Kudeleva G V, Ose V P

出版信息

Vopr Onkol. 1984;30(1):76-85.

PMID:6320544
Abstract

The leukemogenic properties of bovine leukemia virus (BLV), isolated from blood plasma, milk and short-term cultures of blood-circulating leukocytes were studied. A complex life-time examination of 14 calves inoculated with a preparation of BLV established leukemia in 4 animals; it was suspected in 3 calves. By the present time leukemia has been morphologically established in 6 out of 13 calves and one was a suspect. Positive results point directly to the viral etiology of bovine leukemia.

摘要

对从血浆、牛奶和血液循环白细胞短期培养物中分离出的牛白血病病毒(BLV)的致白血病特性进行了研究。对14头接种BLV制剂的小牛进行了为期较长的综合检查,4头动物患白血病;3头小牛疑似患病。目前,13头小牛中有6头在形态学上被确诊患有白血病,1头疑似患病。阳性结果直接指向牛白血病的病毒病因。

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