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Characterization and autoradiographic localization of TRH receptors in sections of rat brain.

作者信息

Pilotte N S, Sharif N A, Burt D R

出版信息

Brain Res. 1984 Feb 20;293(2):372-6. doi: 10.1016/0006-8993(84)91246-0.

DOI:10.1016/0006-8993(84)91246-0
PMID:6320975
Abstract

Receptors for thyrotropin-releasing hormone (TRH) in rat brain have been localized autoradiographically by exposing tritium-sensitive film to sections labeled with [3H]3-Me-His2-TRH. Greatest grain density was found over certain nuclei of the amygdala, with considerable density over several other forebrain areas. Properties of TRH receptor binding in frozen sections closely resembled those of receptors in fresh membrane fragments.

摘要

相似文献

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Characterization and autoradiographic localization of TRH receptors in sections of rat brain.
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2
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Gut. 2002 Jul;51 Suppl 1(Suppl 1):i45-9. doi: 10.1136/gut.51.suppl_1.i45.
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Characterization and distribution of prolactin releasing peptide (PrRP) binding sites in the rat--evidence for a novel binding site subtype in cardiac and skeletal muscle.大鼠中催乳素释放肽(PrRP)结合位点的表征与分布——心脏和骨骼肌中新型结合位点亚型的证据
Br J Pharmacol. 2000 Apr;129(8):1787-93. doi: 10.1038/sj.bjp.0703266.
3
Effects of hypothyroidism on the karyometric development of pyramidal neurons of the hippocampus (CA1), area 6 and area 17 in the male mouse.
甲状腺功能减退对雄性小鼠海马体(CA1)、6区和17区锥体神经元核测量发育的影响。
J Anat. 1987 Feb;150:23-9.
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Regulatory peptide receptors: visualization by autoradiography.
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Neuropeptides TRH and cyclo(His-Pro) share neuromodulatory, but not stimulatory, action on hypothalamic neurons in vitro: implication for the regulation of feeding.神经肽促甲状腺激素释放激素(TRH)和环(组氨酸-脯氨酸)[cyclo(His-Pro)] 对体外培养的下丘脑神经元具有神经调节作用而非刺激作用:对进食调节的启示
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