Barac-Nieto M, Spurr G B, Maksud M G, Lotero H
J Appl Physiol Respir Environ Exerc Physiol. 1978 Feb;44(2):209-15. doi: 10.1152/jappl.1978.44.2.209.
Maximal O2 consumption (VO2max) and maximal endurance time at 80% Vo2max (T80) were determined in 49 subjects with varying degrees of nutritional compromise. Vo2max was lover by 21% and 52% in subjects with moderate and severe undernutrition, respectively, when compared to men with mild nutritional compromise. Most (80%) of the change in Vo2max could be related to the estimated differences in muscle cell mass (MCM). A significant reduction (-18%) in the Vo2max per unit of MCM was found in the severely undernourished subjects, indicating basic physiological changes. Total body hemoglobin showed the highest correlation with Vo2max (r = 0.709) and at constant MCM (partial r = 0.796). A multiple regression equation was derived to estimate the Vo2max of populations on the basis of simple anthropometry and blood hemoglobin levels. T80 (93-103 min) and estimated maximum sustained 8-h percent effort (32%) in mild, intermediate, or severe undernutrition were not significantly different; by contrast, endurance at a given absolute work load was markedly lower in severe undernutrition (8 vs. 1.5 h) due presumably to the difference in Vo2max.
对49名营养状况不同程度受损的受试者测定了最大摄氧量（VO2max）和80%VO2max时的最大耐力时间（T80）。与轻度营养受损的男性相比，中度和重度营养不良受试者的VO2max分别降低了21%和52%。VO2max的变化中大部分（80%）可能与肌肉细胞质量（MCM）的估计差异有关。在严重营养不良的受试者中，发现每单位MCM的VO2max显著降低（-18%），表明存在基本的生理变化。全身血红蛋白与VO2max的相关性最高（r = 0.709），在MCM恒定的情况下（偏r = 0.796）也是如此。根据简单人体测量和血液血红蛋白水平推导出一个多元回归方程，以估计人群的VO2max。轻度、中度或重度营养不良患者的T80（93 - 103分钟）和估计的8小时最大持续用力百分比（32%）没有显著差异；相比之下，由于VO2max的差异，严重营养不良患者在给定绝对工作负荷下的耐力明显较低（8小时对1.5小时）。
