猿猴病毒40增强子和启动子元件诱导染色质结构改变
Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements.
作者信息
Jongstra J, Reudelhuber T L, Oudet P, Benoist C, Chae C B, Jeltsch J M, Mathis D J, Chambon P
出版信息
Nature. 1984;307(5953):708-14. doi: 10.1038/307708a0.
DOI:10.1038/307708a0
PMID:6321997
Abstract
Two simian virus 40 transcriptional promoter elements, the 72-base pair (bp) repeat and the 21-bp repeat region, induce chromatin structures of increased DNase I sensitivity when transposed elsewhere in the viral genome. The induction of a sufficiently long stretch of DNase I-sensitive chromatin leads to the appearance of a visible nucleosome-free region.
摘要
两种猿猴病毒40转录启动子元件，即72碱基对（bp）重复序列和21 bp重复区域，当转座到病毒基因组的其他位置时，会诱导出对DNA酶I敏感性增加的染色质结构。足够长的一段对DNA酶I敏感的染色质的诱导会导致出现一个可见的无核小体区域。
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