丝氨酸蛋白酶在人类营养不良性肌肉中的异常表达。
Abnormal expression of a serine protease in human dystrophic muscle.
作者信息
Katunuma N, Yasogawa N, Kito K, Sanada Y, Kawai H, Miyoshi K
出版信息
J Biochem. 1978 Feb;83(2):625-8. doi: 10.1093/oxfordjournals.jbchem.a131950.
Abstract
The activities of serine protease in muscles from normal persons and from patients with progressive muscular and neuromuscular diseases have been determined. A significant increase in the level of serine protease was found in muscle of patients with Duchenne-type muscular dystrophy and with Becker-type muscular dystrophy, but the activity was not increased in muscle of a patient with amyotrophic lateral sclerosis.
摘要
已测定正常人和进行性肌肉与神经肌肉疾病患者肌肉中丝氨酸蛋白酶的活性。在杜兴型肌营养不良症和贝克型肌营养不良症患者的肌肉中发现丝氨酸蛋白酶水平显著升高，但在肌萎缩侧索硬化症患者的肌肉中该活性并未增加。
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