Kendall B, Harrison M, Schneidau A
Acta Radiol Diagn (Stockh). 1983;24(6):507-10. doi: 10.1177/028418518302400614.
Iohexol containing 180 mg I/ml was used in 20 patients for lumbar myelography. By using an adequate volume up to a maximum of 15 ml, satisfactory films were obtained in all cases. Minor or moderate adverse effects occurred in 4 patients. There were no changes in vital signs or neurologic examination related to the examinations. No patient had difficulty with concentration, personality changes or seizures. Later encephalographies performed in all patients before and during 24 h after the iohexol injections, showed no seizure or abnormal activity or any significant change. Repeated lumbar puncture was performed in 9 patients 24 h after the injection of iohexol. One of these, a patient with symptoms due to disc prolapse, whose CSF was abnormal before the myelography, had a slightly increased cellular response. There was no significant change in any of the other patients. Iohexol is a very satisfactory contrast medium for myelography and compared favorably with other non-ionic contrast media.
含碘量为180毫克/毫升的碘海醇用于20例患者的腰椎脊髓造影。通过使用适量造影剂，最大用量达15毫升，所有病例均获得满意的影像。4例患者出现轻微或中度不良反应。检查过程中生命体征及神经系统检查均无变化。无患者出现注意力不集中、性格改变或癫痫发作。在所有患者碘海醇注射前及注射后24小时内进行的脑电图检查均未显示癫痫发作、异常活动或任何显著变化。9例患者在注射碘海醇24小时后进行了重复腰椎穿刺。其中1例因椎间盘突出出现症状的患者，脊髓造影前脑脊液异常，其细胞反应略有增加。其他患者均无显著变化。碘海醇是一种非常令人满意的脊髓造影造影剂，与其他非离子型造影剂相比具有优势。
