Arnbjörnsson E, Bengmark S
Am J Surg. 1984 Mar;147(3):390-2. doi: 10.1016/0002-9610(84)90174-0.
The role of obstruction in the pathogenesis of acute appendicitis was studied by measuring the pressure in the appendix perioperatively in 24 patients operated on with an appendectomy because of suspected acute appendicitis. The technique used involved inserting a fine needle through the apex into the appendix lumen and measuring the hydrostatic pressure required to inject saline solution. In three patients with a gangrenous appendix found at operation, and in two patients with a phlegmonous appendix, there were signs of obstruction of the appendix lumen as revealed by increased pressure within it. In 14 patients with a phlegmonous appendix found at operation, no signs of obstruction were found. These experimental data suggest that obstruction is not an important causative agent of acute appendicitis, but might develop as a result of the inflammatory process.
通过对24例因疑似急性阑尾炎接受阑尾切除术的患者在围手术期测量阑尾压力，研究梗阻在急性阑尾炎发病机制中的作用。所采用的技术是将一根细针经阑尾尖端插入阑尾腔，并测量注入盐溶液所需的静水压力。在手术中发现的3例坏疽性阑尾炎患者和2例蜂窝织炎性阑尾炎患者中，阑尾腔内压力升高表明存在阑尾腔梗阻迹象。在手术中发现的14例蜂窝织炎性阑尾炎患者中，未发现梗阻迹象。这些实验数据表明，梗阻不是急性阑尾炎的重要致病因素，但可能是炎症过程的结果。
