Gosney J R
J Pathol. 1984 Mar;142(3):163-8. doi: 10.1002/path.1711420303.
The effect of hypobaric hypoxia on the corticotroph population of the adenohypophysis has been studied in male rats. After 28 days exposure to a barometric pressure of 380 mm Hg, equivalent to an altitude of 5500 m, there was an increase in their number relative to the total cell population. This may reflect a requirement for a sustained increase in the level of adrenocortical secretion in an hypoxic environment. Alternatively, higher levels of ACTH may be required to maintain normal levels of adrenocortical hormone secretion under these conditions.
在雄性大鼠中研究了低压缺氧对腺垂体促肾上腺皮质激素细胞群体的影响。在暴露于相当于海拔5500米的380毫米汞柱气压28天后，相对于总细胞群体，它们的数量有所增加。这可能反映了在缺氧环境中肾上腺皮质分泌水平持续增加的需求。或者，在这些条件下可能需要更高水平的促肾上腺皮质激素来维持肾上腺皮质激素分泌的正常水平。
