Heller J E, Konnak J W, Lau Y K
J Urol. 1984 May;131(5):911-3. doi: 10.1016/s0022-5347(17)50707-7.
We studied 44 patients with calcium urolithiasis on high (900 mg. daily) and low (400 mg. daily) calcium diets. With 24-hour urinary data, we categorized the patients as normocalciuric or hypercalciuric and subdivided the hypercalciuric patients into absorptive and renal types. Abbreviated tests, including the 2-hour fasting urinary calcium-to-creatinine ratio and 24-hour urinary (nephrogenous) cyclic adenosine monophosphate, did not predict accurately whether hypercalciuria was of the idiopathic, absorptive or renal type. However, 24-hour urinary calcium excretions on the low calcium diet had a sensitivity and specificity of more than 90 per cent for reproducing the categorized diagnoses.
我们对44例钙结石患者进行了高钙饮食（每日900毫克）和低钙饮食（每日400毫克）研究。根据24小时尿液数据，我们将患者分为正常钙尿型或高钙尿型，并将高钙尿型患者进一步细分为吸收型和肾型。包括2小时空腹尿钙与肌酐比值和24小时尿（肾源性）环磷酸腺苷在内的简化检测，无法准确预测高钙尿症是特发性、吸收型还是肾型。然而，低钙饮食时的24小时尿钙排泄量对重现分类诊断的敏感性和特异性均超过90%。
