Khaustov V I, Korolev M B, Orlova E V, Shekoian L A
Vopr Virusol. 1984 Jan-Feb;29(1):97-103.
Several methodical approaches (negative staining, filtration by rotation, modeling, optic diffraction, and filtration of images) were used to study the structure of ther internal capsid of rotavirus and the structure and mutual arrangement of capsomers comprising it. The internal capsid of rotaviruses was shown to be constructed as a skew icosadeltahedron (left) with T-13 and to consist of 12 pentamers and 120 hexamers. The structural units (a total of 780) comprising capsomers are organized into trimers, each trimer participating in the formation of three adjacent capsomers, while each of the structural units is a part of only one capsomer.
采用了几种系统的方法(负染色、旋转过滤、建模、光学衍射和图像过滤)来研究轮状病毒内壳的结构以及构成内壳的壳粒的结构和相互排列。结果表明,轮状病毒的内壳构建为具有T-13的偏斜二十面体(左),由12个五聚体和120个六聚体组成。构成壳粒的结构单元(共780个)被组织成三聚体,每个三聚体参与形成三个相邻的壳粒,而每个结构单元仅作为一个壳粒的一部分。