Wittek A E, Yeager A S, Au D S, Hensleigh P A
Am J Dis Child. 1984 May;138(5):439-42. doi: 10.1001/archpedi.1984.02140430017005.
Asymptomatic shedding of herpes simplex virus (HSV) was detected in 0.83% of 955 cultures obtained from pregnant women with culture-proved recurrent genital HSV infections during pregnancy; seven (2.3%) of 299 women had asymptomatic shedding. In addition, one (2.3%) of 42 pregnant women with recurrent genital infection in the past but no attacks during pregnancy shed HSV when asymptomatic. Shedding occurred more frequently from the usual lesion site than from the cervix. The virus was not isolated at delivery from women with asymptomatic antepartum shedding. When an active lesion was present, concomitant shedding of HSV from the cervix occurred in seven (3.6%) of 193 pregnant women with vulvar lesions and in one (2.1%) of 47 women with lesions remote from the vulva. Ninety-two percent of the latter lesions were caused by type 2 HSV. In women who have had recurrent genital HSV infections in the past, asymptomatic shedding occurs in those with active attacks during pregnancy as well as in those asymptomatic throughout pregnancy; however, asymptomatic shedding during the antepartum period does not predict asymptomatic shedding at delivery.
在955份取自孕期有培养证实的复发性生殖器疱疹病毒（HSV）感染的孕妇的培养物中，0.83%检测到HSV无症状排毒；299名女性中有7名（2.3%）有无症状排毒。此外，42名既往有复发性生殖器感染但孕期无发作的孕妇中有1名（2.3%）在无症状时排出HSV。排毒在通常的病灶部位比在宫颈更频繁发生。无症状产前排毒的女性在分娩时未分离出病毒。当存在活动性病灶时，193名有外阴病灶的孕妇中有7名（3.6%）以及47名病灶远离外阴的女性中有1名（2.1%）宫颈同时排出HSV。后者92%的病灶由2型HSV引起。在既往有复发性生殖器HSV感染的女性中，孕期有活动性发作的以及整个孕期无症状的都会发生无症状排毒；然而，产前无症状排毒并不能预测分娩时无症状排毒。
