Postma P W, Epstein W, Schuitema A R, Nelson S O
J Bacteriol. 1984 Apr;158(1):351-3. doi: 10.1128/jb.158.1.351-353.1984.
Purified IIIGlc of the phosphoenolpyruvate:sugar phosphotransferase system of Salmonella typhimurium inhibits glycerol kinase. Phosphorylation of IIIGlc via phosphoenolpyruvate, enzyme I, and HPr abolishes this inhibition. The glycerol facilitator is not inhibited by IIIGlc. It is proposed that regulation of glycerol metabolism by the phosphoenolpyruvate:sugar phosphotransferase system is at the level of glycerol kinase.
糖磷酸转移酶系统的纯化IIIGlc抑制甘油激酶。通过磷酸烯醇丙酮酸、酶I和HPr对IIIGlc进行磷酸化可消除这种抑制作用。甘油转运体不受IIIGlc抑制。有人提出,磷酸烯醇丙酮酸:糖磷酸转移酶系统对甘油代谢的调节作用是在甘油激酶水平上。