Futaki T, Oda M
Jpn J Antibiot. 1983 Oct;36(10):2675-82.
Clinical efficacy and safety of cefotiam were studied. Twelve patients with chronic sinusitis and 14 patients with chronic otitis media were intravenously given cefotiam in daily doses of 2 g for 7 to 10 days. In chronic sinusitis, clinical responses were excellent in 6 patients, good in 3 and fair in 3, the rate of satisfactory clinical responses (excellent and good) being 75%. In chronic otitis media, the responses were excellent in 5, good in 4 and fair in 5, the rate of satisfactory clinical responses being 65%. As for side effects, eruption and abdominal pain were observed in 1 patient.
研究了头孢替安的临床疗效和安全性。12例慢性鼻窦炎患者和14例慢性中耳炎患者静脉注射头孢替安，每日剂量2g，疗程7至10天。在慢性鼻窦炎患者中，6例临床反应极佳，3例良好，3例尚可，临床反应满意（极佳和良好）率为75%。在慢性中耳炎患者中，5例反应极佳，4例良好，5例尚可，临床反应满意率为65%。至于副作用，1例患者出现皮疹和腹痛。
