Takeda K, Yoshida M, Ishida T
Jpn J Antibiot. 1983 Oct;36(10):2715-20.
Cefotiam (CTM) was intravenously given to 20 patients with infections in the field of otorhinolaryngology. Daily doses of CTM were 2 to 4 g divided into 2. Clinical responses were excellent in 11 patients, good in 8 and fair in 1, the rate of satisfactory clinical responses being 95% (19/20). Ninety-one % (10/11) of Gram-positive cocci isolated from the patients were eradicated by the CTM treatment, while 60% (6/10) of Gram-negative bacilli were persisted. As for the side effects, eruption and elevation of GOT and GPT were observed in 1 patient.
对20例耳鼻喉科感染患者静脉注射头孢替安（CTM）。CTM的日剂量为2至4克，分2次给药。11例患者临床反应优秀，8例良好，1例一般，临床反应满意率为95%（19/20）。CTM治疗清除了患者分离出的革兰氏阳性球菌的91%（10/11），而革兰氏阴性杆菌有60%（6/10）持续存在。至于副作用，1例患者出现皮疹以及谷草转氨酶和谷丙转氨酶升高。
