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钴对豚鼠输精管对外源性去甲肾上腺素和场刺激的电反应及机械反应的影响。

Effect of cobalt on electrical and mechanical responses to exogenous noradrenaline and to field stimulations in the guinea-pig vas deferens.

作者信息

Wakui M, Inomata H

出版信息

Jpn J Physiol. 1983;33(6):1057-60. doi: 10.2170/jjphysiol.33.1057.

DOI:10.2170/jjphysiol.33.1057
PMID:6325786
Abstract

Co2+ suppressed the mechanical responses evoked by field stimulations and by application of noradrenaline (NA) in the smooth muscle of guinea-pig vas deferens. However, the membrane excitation and force development evoked by depolarizing currents were not much affected in the Co2+ treatment. It is proposed that Co2+ suppresses NA induced contraction by inhibiting the development of the membrane depolarization.

摘要

Co2+抑制了豚鼠输精管平滑肌中电场刺激和去甲肾上腺素（NA）作用所诱发的机械反应。然而，在Co2+处理下，去极化电流所诱发的膜兴奋和力量产生并未受到太大影响。有人提出，Co2+通过抑制膜去极化的发展来抑制NA诱导的收缩。

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