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[阿司匹林可溶性前体在骨科手术中的镇痛活性评估]

[Evaluation of the analgesic activity of a soluble precursor of aspirin in orthopedic surgery].

作者信息

Letenneur J

出版信息

Sem Hop. 1984 Apr 5;60(15):1089-91.

PMID:6326301
Abstract

We carried out a randomized double-blind trial to evaluate the analgesic effect, rapidity of action and tolerance of calcium carbasalate relative to a placebo, given in a single dose of 1 gr. aspirin equivalent immediately after an orthopedic surgical procedure. Autoevaluation by the patient using a visual scale and overall evaluation of analgesic effectiveness by the patient and relatives showed that pain was significantly less with the active therapy whose tolerance was excellent.

摘要

我们进行了一项随机双盲试验,以评估相对于安慰剂,卡巴匹林钙在骨科手术后立即单剂量给予1克阿司匹林等效物时的镇痛效果、起效速度和耐受性。患者使用视觉量表进行自我评估,以及患者和亲属对镇痛效果的总体评估显示,活性治疗组的疼痛明显减轻,且耐受性极佳。

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