McPherson M A, Pickering B T
J Endocrinol. 1978 Mar;76(3):461-71. doi: 10.1677/joe.0.0760461.
A number of antisera have been raised against individual rat neurophysins. One of these proved suitable for the specific radioimmunoassay of rat vasopressin-neurophysin and data validating such a use are presented. Use of this antiserum showed that vasopressin-neurophysin is present in rat neurohypophyses in equimolar amounts to vasopressin, while in the hypothalamus the assay detected twice as much neurophysin-like material as hormone. A number of partially specific antisera for rat oxytocin-neurophysin have been obtained and the best of these was raised against the minor neurophysin.
已经制备了多种针对个别大鼠神经垂体素的抗血清。其中一种被证明适用于大鼠加压素 - 神经垂体素的特异性放射免疫测定，并给出了验证这种用途的数据。使用这种抗血清表明，加压素 - 神经垂体素在大鼠神经垂体中与加压素以等摩尔量存在，而在下丘脑中，该测定检测到的神经垂体素样物质是激素的两倍。已经获得了多种针对大鼠催产素 - 神经垂体素的部分特异性抗血清，其中最好的是针对次要神经垂体素制备的。
