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[长期外照射γ射线后犬肝脏肿瘤的晚期发生]

[Late development of tumors in the liver of dogs after long-term external gamma-radiation].

作者信息

Iakovleva V I

出版信息

Radiobiologiia. 1984 Mar-Apr;24(2):269-73.

PMID:6328570
Abstract

Development of tumors in the liver of dogs exposed to gamma-quanta for 3 and 6 years at dose--rates of 0.0006, 0.0017 and 0.0034 Gy/day was studied 1-10 years after termination of the exposure. The results are summarized in this work. Tumors were found in 27 out of 89 dogs. The number of benign and malignant tumors was virtually the same (13 and 14). In the first place were hepatoma, among benign neoplasms (9 out of 13), and liver cancer, among malignant tumors (12 out of 14). Neoplasms were more frequent (32%) in exposed animals than in the controls (19%). Tumors were almost two times more frequent and developed earlier after 6 year- than after-3-year-irradiation.

摘要

研究了在剂量率为0.0006、0.0017和0.0034 Gy/天的条件下,接受γ量子照射3年和6年的犬肝脏肿瘤的发生情况,照射终止后1至10年进行观察。本文总结了研究结果。89只犬中有27只发现肿瘤。良性和恶性肿瘤数量几乎相同(分别为13个和14个)。良性肿瘤中以肝细胞瘤居多(13个中有9个),恶性肿瘤中以肝癌居多(14个中有12个)。受照射动物的肿瘤发生率(32%)高于对照组(19%)。照射6年后肿瘤发生率几乎是照射3年后的两倍,且肿瘤发生时间更早。

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