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[培养的大鼠胸膜间皮细胞中苯并(a)芘的代谢]

[Metabolism of benzo(a)pyrene in rat pleural mesothelial cells in culture].

作者信息

Sigeac I B, Habart M H, Jaurand M C, Bignon J

出版信息

C R Acad Sci III. 1984;298(15):423-6.

PMID:6329489
Abstract

Cultures of Rat pleural mesothelial cells obtained after isolation of parietal cells metabolized benzo(a)pyrene to organosoluble and hydrosoluble derivatives. This property is well maintained since it was observed with cells at 6th passage as well as after 39 passages.

摘要

分离壁层细胞后获得的大鼠胸膜间皮细胞培养物可将苯并(a)芘代谢为有机可溶性和水溶性衍生物。自第6代细胞以及39代细胞后观察到该特性以来，此特性一直保持良好。

相似文献

1
[Metabolism of benzo(a)pyrene in rat pleural mesothelial cells in culture].[培养的大鼠胸膜间皮细胞中苯并(a)芘的代谢]
C R Acad Sci III. 1984;298(15):423-6.
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Metabolism of benzo(a)pyrene by human epithelial and fibroblastic cells: metabolite patterns and DNA adduct formation.人上皮细胞和成纤维细胞对苯并(a)芘的代谢：代谢物模式与DNA加合物的形成
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Metabolism and macromolecular binding of carcinogenic and noncarcinogenic metabolites of benzo(a)pyrene by hamster embryo cells.仓鼠胚胎细胞对苯并(a)芘致癌和非致癌代谢产物的代谢及大分子结合
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Binding of benzo(a)pyrene derivatives to specific proteins in nuclei of intact hamster embryo cells.苯并（a）芘衍生物与完整仓鼠胚胎细胞核中特定蛋白质的结合。
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Cancer Res. 1975 Dec;35(12):3551-7.

引用本文的文献

1
Sister chromatid exchanges in rat pleural mesothelial cells treated with crocidolite, attapulgite, or benzo 3-4 pyrene.用青石棉、凹凸棒石或苯并芘处理的大鼠胸膜间皮细胞中的姐妹染色单体交换
Br J Ind Med. 1987 Apr;44(4):281-3. doi: 10.1136/oem.44.4.281.