苯并(a)芘在源自大鼠气管的器官和细胞培养物中的代谢比较 - Suppr

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Comparative metabolism of benzo(a)pyrene in organ and cell cultures derived from rat tracheas.

作者信息

Cohen G M, Marchok A C, Nettesheim P, Steele V E, Nelson F, Huang S, Selkirk J K

出版信息

Cancer Res. 1979 Jun;39(6 Pt 1):1980-4.

PMID:445397

Abstract

摘要

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Comparative metabolism of benzo(a)pyrene in organ and cell cultures derived from rat tracheas.苯并(a)芘在源自大鼠气管的器官和细胞培养物中的代谢比较

Cancer Res. 1979 Jun;39(6 Pt 1):1980-4.

A comparison between the activation of benzo[a]pyrene in organ cultures and microsomes from the tracheal epithelium of rats and hamsters.大鼠和仓鼠气管上皮器官培养物与微粒体中苯并[a]芘激活情况的比较。

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Metabolism of benzo(a)pyrene and its major metabolites to ethyl acetate-soluble and water-soluble metabolites by cultured rodent trachea.培养的啮齿动物气管对苯并(a)芘及其主要代谢产物向乙酸乙酯可溶性和水溶性代谢产物的代谢作用。

Cancer Res. 1978 Sep;38(9):3066-75.

[3H]Benzo(a)pyrene metabolism in tracheal epithelial microsomes and tracheal organ cultures.气管上皮微粒体和气管器官培养物中[3H]苯并(a)芘的代谢

Cancer Res. 1978 Nov;38(11 Pt 1):3861-6.

Metabolism of ether-linked glycerolipids in cultures of normal and neoplastic rat respiratory tract epithelium.正常和肿瘤性大鼠呼吸道上皮细胞培养物中醚键连接甘油脂的代谢

Cancer Res. 1979 Jan;39(1):207-14.

Hexose uptake in 7,12-dimethylbenz(a)anthracene-preexposed rat tracheal epithelial cells during the progression of neoplasia.在肿瘤形成过程中，7,12-二甲基苯并(a)蒽预先暴露的大鼠气管上皮细胞中的己糖摄取情况。

Cancer Res. 1984 Jul;44(7):3081-9.

Metabolism and covalent binding of [3H]benzo(a)pyrene by isolated perfused lungs and short-term tracheal organ culture of cigarette smoke-exposed rats.

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[Metabolism of benzo(a)pyrene in rat pleural mesothelial cells in culture].[培养的大鼠胸膜间皮细胞中苯并(a)芘的代谢]

C R Acad Sci III. 1984;298(15):423-6.

Induction of preneoplastic and neoplastic lesions in grafted rat tracheas continuously exposed to benzo(a)pyrene.在持续暴露于苯并(a)芘的移植大鼠气管中诱发癌前病变和肿瘤性病变。

Cancer Res. 1977 May;37(5):1272-8.

Metabolism and binding of benzo(a)pyrene and 2-acetylaminofluorene by short-term organ cultures of human and rat bladder.苯并(a)芘和2-乙酰氨基芴在人和大鼠膀胱短期器官培养中的代谢与结合

Cancer Res. 1982 Feb;42(2):642-8.

引用本文的文献

Detection of chemical carcinogens by assay of unscheduled DNA synthesis in rat tracheal epithelium in short-term organ culture.通过短期器官培养中大鼠气管上皮细胞非程序性DNA合成检测化学致癌物。

J Cancer Res Clin Oncol. 1981;102(2):115-26. doi: 10.1007/BF00410663.

Quantitation of cell proliferation, colony formation, and carcinogen induced cytotoxicity of rat tracheal epithelial cells grown in culture on 3T3 feeder layers.在3T3饲养层上培养的大鼠气管上皮细胞的细胞增殖、集落形成及致癌物诱导的细胞毒性的定量分析。

In Vitro. 1983 Jul;19(7):559-70. doi: 10.1007/BF02619604.

Metabolism of benzo[a]pyrene by human mammary epithelial cells: toxicity and DNA adduct formation.人乳腺上皮细胞对苯并[a]芘的代谢：毒性与DNA加合物形成

Proc Natl Acad Sci U S A. 1981 Oct;78(10):6251-5. doi: 10.1073/pnas.78.10.6251.

Biochemical studies of the tracheobronchial epithelium.气管支气管上皮的生化研究。

Environ Health Perspect. 1984 Jun;56:61-74. doi: 10.1289/ehp.845661.

Role of inhalation studies with animals in defining human health risks for vehicle and power plant emissions.动物吸入研究在确定车辆和发电厂排放对人类健康风险方面的作用。

Environ Health Perspect. 1983 Jan;47:283-92. doi: 10.1289/ehp.8347283.

Differentiation of cultured epithelial cells: response to toxic agents.培养上皮细胞的分化：对毒性剂的反应。

Environ Health Perspect. 1989 Mar;80:239-46. doi: 10.1289/ehp.8980239.

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