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β-内啡肽片段6-31对吗啡和β-内啡肽诱导的生长激素及催乳素释放的影响。

Effects of beta-endorphin fragment 6-31 on morphine- and beta-endorphin-induced growth hormone and prolactin release.

作者信息

Panerai A E, Cocchi D, Parenti M, Martini A, Mantegazza P, Li C H

出版信息

Eur J Pharmacol. 1984 Apr 6;99(4):341-3. doi: 10.1016/0014-2999(84)90143-2.

DOI:10.1016/0014-2999(84)90143-2
PMID:6329787
Abstract

A fragment of human beta-endorphin (beta h-EP-(6-31] has been proposed as an endogenous inhibitor of beta-endorphin. We have evaluated the effects of the fragment on beta-endorphin- and morphine-induced prolactin and growth hormone release. It inhibited both morphine- and beta-endorphin-induced prolactin release, while it was ineffective on the release of growth hormone.

摘要

人β-内啡肽片段(βh-EP-(6-31])被认为是β-内啡肽的内源性抑制剂。我们评估了该片段对β-内啡肽和吗啡诱导的催乳素及生长激素释放的影响。它抑制了吗啡和β-内啡肽诱导的催乳素释放,但对生长激素的释放没有作用。

相似文献

1
Effects of beta-endorphin fragment 6-31 on morphine- and beta-endorphin-induced growth hormone and prolactin release.β-内啡肽片段6-31对吗啡和β-内啡肽诱导的生长激素及催乳素释放的影响。
Eur J Pharmacol. 1984 Apr 6;99(4):341-3. doi: 10.1016/0014-2999(84)90143-2.
2
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Peptide inhibitor of morphine- and beta-endorphin-induced analgesia.吗啡和β-内啡肽诱导镇痛的肽类抑制剂。
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Morphine does not stimulate prolactin release during lactation.
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Analgesic effect of morphine: a role for beta-endorphin.吗啡的镇痛作用:β-内啡肽的作用
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