β-内啡肽片段6-31对吗啡和β-内啡肽诱导的生长激素及催乳素释放的影响。
Effects of beta-endorphin fragment 6-31 on morphine- and beta-endorphin-induced growth hormone and prolactin release.
作者信息
Panerai A E, Cocchi D, Parenti M, Martini A, Mantegazza P, Li C H
出版信息
Eur J Pharmacol. 1984 Apr 6;99(4):341-3. doi: 10.1016/0014-2999(84)90143-2.
PMID:6329787
Abstract
A fragment of human beta-endorphin (beta h-EP-(6-31] has been proposed as an endogenous inhibitor of beta-endorphin. We have evaluated the effects of the fragment on beta-endorphin- and morphine-induced prolactin and growth hormone release. It inhibited both morphine- and beta-endorphin-induced prolactin release, while it was ineffective on the release of growth hormone.
摘要
人β-内啡肽片段（βh-EP-(6-31]）被认为是β-内啡肽的内源性抑制剂。我们评估了该片段对β-内啡肽和吗啡诱导的催乳素及生长激素释放的影响。它抑制了吗啡和β-内啡肽诱导的催乳素释放，但对生长激素的释放没有作用。
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