Nielsen V K, Jannetta P J
Neurology. 1984 Jul;34(7):891-7. doi: 10.1212/wnl.34.7.891.
We studied 59 patients with hemifacial spasm before decompression of the facial nerve in the cerebellopontine angle. Fifty-three patients were reexamined 1 week later, and 30 patients after 2 to 8 months. Within 1 week, ephaptic transmission disappeared in 23% and changed from bidirectional to unidirectional in 45%. After-discharges disappeared in 64% and were mild in 34%. Synkinesis after supraorbital nerve stimulation disappeared in 53%, and the blink reflex amplitude became normal. After 2 to 8 months, ephaptic transmission was abolished in 73% and unidirectional in 17%. After-discharges and synkinesis disappeared in 90%, and the latency of the blink reflex decreased. It is concluded that decompression stops ectopic/ ephaptic excitation due to decrease in the interstitial resistance, and enables remyelination.
我们对59例在小脑脑桥角进行面神经减压术前的面肌痉挛患者进行了研究。53例患者在1周后接受复查，30例患者在2至8个月后接受复查。在1周内，23%的患者触觉性传递消失，45%的患者从双向变为单向。64%的患者后放电消失，34%的患者后放电较轻。眶上神经刺激后的联带运动在53%的患者中消失，眨眼反射幅度恢复正常。在2至8个月后，73%的患者触觉性传递消失，17%的患者为单向。90%的患者后放电和联带运动消失，眨眼反射潜伏期缩短。结论是，减压通过降低组织间电阻阻止异位/触觉性兴奋，并促进髓鞘再生。
