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荷兰脊髓灰质炎的监测与控制

Surveillance and control of poliomyelitis in The Netherlands.

作者信息

Bijkerk H

出版信息

Rev Infect Dis. 1984 May-Jun;6 Suppl 2:S451-6. doi: 10.1093/clinids/6.supplement_2.s451.

Abstract

Inactivated poliovirus vaccine was introduced to the national immunization program in The Netherlands in 1957. A compliance rate of approximately 95% has existed since 1967. Only one of the 148 reported cases of paralytic poliomyelitis (from 1966 to 1982) occurred in an individual who had been vaccinated against poliomyelitis. Apart from sporadic imported cases, local outbreaks as well as an epidemic in 1978 were observed among certain susceptible Protestant populations. These unvaccinated groups, whose members--scattered as they are among the Dutch population--form a closed community, have to be considered at high-risk as long as importation of wild poliovirus strains occurs regularly. Endemic persistence of wild poliovirus in The Netherlands has, however, virtually disappeared. Potent inactivated poliovirus vaccine appears to be highly immunogenic and confers protection of long duration.

摘要

1957年,荷兰将灭活脊髓灰质炎疫苗纳入国家免疫规划。自1967年以来,疫苗接种率约为95%。在1966年至1982年报告的148例麻痹性脊髓灰质炎病例中,只有1例发生在接种过脊髓灰质炎疫苗的个体身上。除了散在的输入性病例外,在某些易感的新教人群中还观察到了局部暴发以及1978年的一次流行。这些未接种疫苗的群体,其成员分散在荷兰人口中,形成了一个封闭的社区,只要野生脊髓灰质炎病毒株定期输入,就必须被视为高危群体。然而,野生脊髓灰质炎病毒在荷兰的地方性持续传播实际上已经消失。强效灭活脊髓灰质炎疫苗似乎具有高度免疫原性,并能提供长期保护。

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