脊髓灰质炎病毒的分子遗传学

Molecular genetics of poliovirus.

作者信息

Baltimore D

出版信息

Rev Infect Dis. 1984 May-Jun;6 Suppl 2:S484-6. doi: 10.1093/clinids/6.supplement_2.s484.

DOI:10.1093/clinids/6.supplement_2.s484

Abstract

Poliovirus research has reached the point where molecular biologists and those interested in control of the disease can profitably come together. New molecular approaches offer the opportunity to make vaccines by previously inconceivable routes. These include synthesis of antigenic proteins in bacteria and chemical synthesis of antigenic peptides.

摘要

脊髓灰质炎病毒研究已发展到分子生物学家和关注该疾病防治的人员能够有效合作的阶段。新的分子方法提供了通过以前难以想象的途径生产疫苗的机会。这些途径包括在细菌中合成抗原蛋白以及抗原肽的化学合成。