在伯基特淋巴瘤中激活的人类Blym转化基因的核苷酸序列。

Nucleotide sequence of a human Blym transforming gene activated in a Burkitt's lymphoma.

作者信息

Diamond A, Devine J M, Cooper G M

出版信息

Science. 1984 Aug 3;225(4661):516-9. doi: 10.1126/science.6330897.

Abstract

The nucleotide sequence of a human Blym-1 transforming gene activated in a Burkitt's lymphoma cell line was determined. This sequence predicts a small protein of 58 amino acids that is 33 percent identical to the predicted product of chicken Blym-1, the activated transforming gene of chicken B cell lymphomas. Both the human and chicken Blym-1 genes exhibit significant identity to an amino-terminal region of transferrins.

摘要

测定了在伯基特淋巴瘤细胞系中激活的人类Blym-1转化基因的核苷酸序列。该序列预测了一个由58个氨基酸组成的小蛋白，它与鸡Blym-1（鸡B细胞淋巴瘤的激活转化基因）的预测产物有33%的同一性。人类和鸡的Blym-1基因与转铁蛋白的氨基末端区域都有显著的同一性。