Suenson M
Acta Physiol Scand. 1984 Mar;120(3):445-55. doi: 10.1111/j.1748-1716.1984.tb07405.x.
Impulse transmission between closely appositioned cylindrical myocardial preparations , from the ferret, was studied in vitro. One preparation was driven, and when the longitudinal extracellular potential difference between electrodes 80 micrometers apart was made larger than 30-60 mV by increasing the resistance of the extracellular space, ephaptic (i.e. non synaptic) impulse transmission from one preparation to another occurred. In 2 out of 8 pairs of preparations examined the impulse transmission was bidirectional. The latency of the transmission varied from 9 to 369 ms. Various rate dependent blocks (sometimes associated with a Wenckebach phenomenon) were observed at stimulation frequencies above 1 Hz. The experimental situation has pathophysiological properties relevant to the analysis of the genesis of arrhythmias. Ephaptic interaction may be involved in the shaping of the wavefront of excitation under both normal and pathological conditions.
对雪貂紧密并置的圆柱形心肌制剂之间的冲动传递进行了体外研究。一个制剂被驱动，当通过增加细胞外间隙电阻使相距80微米的电极之间的纵向细胞外电位差大于30 - 60 mV时，就会发生从一个制剂到另一个制剂的电紧张性（即非突触性）冲动传递。在检查的8对制剂中有2对的冲动传递是双向的。传递的潜伏期从9到369毫秒不等。在高于1 Hz的刺激频率下观察到各种频率依赖性阻滞（有时与文氏现象有关）。该实验情况具有与心律失常发生机制分析相关的病理生理特性。电紧张性相互作用可能在正常和病理条件下的兴奋波前形成中起作用。
