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Comparative efficacy of cefotiam versus cephalothin in the therapy of skin and soft tissue infections.

作者信息

Lentino J R, Stachowski M, Strikas R, Parrillo P

出版信息

Antimicrob Agents Chemother. 1984 Jun;25(6):778-80. doi: 10.1128/AAC.25.6.778.

Abstract

Cefotiam was evaluated by a comparative open-label randomized trial with cephalothin in the therapy of skin and soft tissue infections in 39 patients. The most common organism isolated was Staphylococcus aureus (78%). We established evidence of primary infection with gram-negative bacilli in four patients, three of whom were diabetic. Eight patients had mixed infections or superinfections. No patient was evaluated as a treatment failure; for 10 of 39 patients we were unable to recover an etiological agent but demonstrated a clinical cure. Cefotiam was found to be as effective as cephalothin in the therapy of skin and soft tissue infections.

摘要

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本文引用的文献

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In-vitro activity of cefotiam against bacteria of clinical interest.
J Antimicrob Chemother. 1982 Nov;10(5):391-5. doi: 10.1093/jac/10.5.391.
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