Weinack O M, Snoeyenbos G H, Smyser C F, Soerjadi-Liem A S
Avian Dis. 1984 Apr-Jun;28(2):416-25.
Chickens that have considerable resistance to Salmonella typhimurium or Escherichia coli infection by early development of a native intestinal microflora shed these bacteria following aerosol exposure to Mycoplasma gallisepticum and/or infectious bronchitis virus. Administration of cyclophosphamide to similarly treated chickens induced slight shedding of these bacteria, and the combination of cyclophosphamide and respiratory agents magnified the shedding rate. These agents also influenced the isolation rate of E. coli and S. typhimurium from the trachea and air sacs.
通过早期形成天然肠道微生物群而对鼠伤寒沙门氏菌或大肠杆菌感染具有相当抵抗力的鸡，在经气溶胶暴露于鸡毒支原体和/或传染性支气管炎病毒后会排出这些细菌。对经过类似处理的鸡施用环磷酰胺会导致这些细菌轻微排出，而环磷酰胺与呼吸道病原体的联合使用会放大排出率。这些病原体还影响了从气管和气囊中分离大肠杆菌和鼠伤寒沙门氏菌的比率。
