• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

大鼠背外侧隔区神经元的细胞内记录,体外实验。

Intracellular recordings from rat dorsolateral septal neurons, in vitro.

作者信息

Stevens D R, Gallagher J P, Shinnick-Gallagher P

出版信息

Brain Res. 1984 Jul 9;305(2):353-6. doi: 10.1016/0006-8993(84)90441-4.

DOI:10.1016/0006-8993(84)90441-4
PMID:6331603
Abstract

We have made intracellular recordings from the dorsolateral septal nucleus (DLSN) in a rat brain slice. DLSN neurons fire short tetrodotoxin (TTX) sensitive action potentials followed by an after-hyperpolarization. The action potential is followed by either a Ca2+-dependent depolarization or a Ca2+-dependent after-hyperpolarization. Stimulation of medial septum results in antidromic invasion of DLSN neurons while stimulation of the fimbria/fornix results in orthodromic EPSPs or action potentials.

摘要

我们在大鼠脑片中对背外侧隔核(DLSN)进行了细胞内记录。DLSN神经元发放对河豚毒素(TTX)敏感的短动作电位,随后出现超极化后电位。动作电位之后要么是Ca2+依赖性去极化,要么是Ca2+依赖性超极化后电位。刺激内侧隔会导致DLSN神经元的逆向入侵,而刺激穹窿/穹窿则会导致顺向兴奋性突触后电位(EPSP)或动作电位。

相似文献

1
Intracellular recordings from rat dorsolateral septal neurons, in vitro.大鼠背外侧隔区神经元的细胞内记录,体外实验。
Brain Res. 1984 Jul 9;305(2):353-6. doi: 10.1016/0006-8993(84)90441-4.
2
Ionic basis of the differential neuronal activity of guinea-pig septal nucleus studied in vitro.豚鼠离体隔核神经元活动差异的离子基础研究
J Physiol. 1988 Feb;396:399-415. doi: 10.1113/jphysiol.1988.sp016969.
3
Bicuculline- and phaclofen-sensitive components of N-methyl-D-aspartate-induced hyperpolarizations in rat dorsolateral septal nucleus neurones.大鼠背外侧隔核神经元中N-甲基-D-天冬氨酸诱导的超极化的荷包牡丹碱和法克洛芬敏感成分。
J Physiol. 1989 Nov;418:367-77. doi: 10.1113/jphysiol.1989.sp017846.
4
Rat lateral septum in slice preparation with viable transmission.
Exp Neurol. 1987 Jan;95(1):1-12. doi: 10.1016/0014-4886(87)90001-x.
5
A calcium-dependent slow afterdepolarization recorded in rat dorsolateral septal nucleus neurons in vitro.在体外记录到的大鼠背外侧隔核神经元中一种钙依赖性慢后去极化。
J Neurophysiol. 1990 Dec;64(6):1838-46. doi: 10.1152/jn.1990.64.6.1838.
6
The hippocampal control of neuronal discharges in the septum of the rat.大鼠隔区神经元放电的海马控制
J Physiol. 1974 Mar;237(3):607-24. doi: 10.1113/jphysiol.1974.sp010500.
7
Facilitatory action of muscarine on the slow afterdepolarization of rat dorsolateral septal nucleus neurons in vitro.
Neurosci Lett. 1990 May 4;112(2-3):234-8. doi: 10.1016/0304-3940(90)90209-r.
8
Localization of tetrodotoxin-sensitive field potentials of CA1 pyramidal cells in the rat hippocampus.大鼠海马体中CA1锥体细胞河豚毒素敏感场电位的定位
J Neurophysiol. 1989 Dec;62(6):1375-87. doi: 10.1152/jn.1989.62.6.1375.
9
Excitatory amino acid-receptor-mediated EPSPs in rat dorsolateral septal nucleus neurones in vitro.体外培养的大鼠背外侧隔核神经元中兴奋性氨基酸受体介导的兴奋性突触后电位
J Physiol. 1989 Nov;418:353-65. doi: 10.1113/jphysiol.1989.sp017845.
10
Properties of rat medial septal neurones recorded in vitro.体外记录的大鼠内侧隔核神经元的特性
J Physiol. 1986 Oct;379:309-30. doi: 10.1113/jphysiol.1986.sp016255.

引用本文的文献

1
Deciphering the peculiarities of cell types in the septum.解读隔膜中细胞类型的特性。
Neuroscience. 2025 Jan 26;565:327-341. doi: 10.1016/j.neuroscience.2024.11.063. Epub 2024 Nov 26.
2
Top-down regulation of motivated behaviors via lateral septum sub-circuits.通过侧隔核亚回路对动机行为进行自上而下的调控。
Mol Psychiatry. 2022 Aug;27(8):3119-3128. doi: 10.1038/s41380-022-01599-3. Epub 2022 May 18.
3
Activation of presynaptic 5-hydroxytryptamine 2A receptors facilitates excitatory synaptic transmission via protein kinase C in the dorsolateral septal nucleus.
突触前5-羟色胺2A受体的激活通过蛋白激酶C促进背外侧隔核中的兴奋性突触传递。
J Neurosci. 2002 Sep 1;22(17):7509-17. doi: 10.1523/JNEUROSCI.22-17-07509.2002.
4
Reduced outward K+ conductances generate depolarizing after-potentials in rat supraoptic nucleus neurones.外向钾离子电导降低在大鼠视上核神经元中产生去极化后电位。
J Physiol. 1997 Nov 15;505 ( Pt 1)(Pt 1):95-106. doi: 10.1111/j.1469-7793.1997.095bc.x.
5
Activation of a metabotropic excitatory amino acid receptor potentiates spike-driven calcium increases in neurons of the dorsolateral septum.代谢型兴奋性氨基酸受体的激活增强了背外侧隔区神经元中峰电位驱动的钙增加。
J Neurosci. 1996 Oct 1;16(19):6079-88. doi: 10.1523/JNEUROSCI.16-19-06079.1996.
6
The role of calcium in the repetitive firing of neostriatal neurons.
Exp Brain Res. 1989;75(1):157-68. doi: 10.1007/BF00248539.
7
Bicuculline- and phaclofen-sensitive components of N-methyl-D-aspartate-induced hyperpolarizations in rat dorsolateral septal nucleus neurones.大鼠背外侧隔核神经元中N-甲基-D-天冬氨酸诱导的超极化的荷包牡丹碱和法克洛芬敏感成分。
J Physiol. 1989 Nov;418:367-77. doi: 10.1113/jphysiol.1989.sp017846.
8
Excitatory amino acid-receptor-mediated EPSPs in rat dorsolateral septal nucleus neurones in vitro.体外培养的大鼠背外侧隔核神经元中兴奋性氨基酸受体介导的兴奋性突触后电位
J Physiol. 1989 Nov;418:353-65. doi: 10.1113/jphysiol.1989.sp017845.
9
Ionic basis of the differential neuronal activity of guinea-pig septal nucleus studied in vitro.豚鼠离体隔核神经元活动差异的离子基础研究
J Physiol. 1988 Feb;396:399-415. doi: 10.1113/jphysiol.1988.sp016969.
10
Pharmacology of nicotinic receptor-mediated inhibition in rat dorsolateral septal neurones.大鼠背外侧隔区神经元中烟碱受体介导的抑制作用的药理学
J Physiol. 1991 May;436:325-46. doi: 10.1113/jphysiol.1991.sp018553.