Chen-Woan M, McGregor D D
Cell Immunol. 1984 Sep;87(2):538-45. doi: 10.1016/0008-8749(84)90022-4.
T cells from peritoneal exudates induced in rats convalescing from a recent infection of Listeria monocytogenes were fractionated into two subsets based on their ability to bind monoclonal antibodies to cell-surface determinants that are expressed on some but not all peripheral T cells. Two phenotypically distinct subsets, one recognized by the antibody MRC OX8 and the other by W3/25, were assayed for their protective capacity in Listeria-challenged recipients, and for their ability to kill unmodified syngeneic fibroblasts in vitro. The two activities were mediated by the OX8+ subset which comprised approximately half the T cells in the exudates.
从近期感染单核细胞增生李斯特菌后正在康复的大鼠腹腔渗出液中获取的T细胞，根据其与单克隆抗体结合的能力，被分为两个亚群，该单克隆抗体针对某些但并非所有外周T细胞表面表达的决定簇。两个表型不同的亚群，一个可被抗体MRC OX8识别，另一个可被W3/25识别，对它们在受到李斯特菌攻击的受体中的保护能力以及在体外杀死未修饰的同基因成纤维细胞的能力进行了检测。这两种活性由OX8+亚群介导，该亚群约占渗出液中T细胞的一半。
