胞壁酰二肽对胸腺细胞对植物血凝素增殖反应的增强作用1。
Augmentation of the proliferative response of thymocytes to phytohemagglutinin by the muramyl dipeptide1.
作者信息
Iribe H, Koga T
出版信息
Cell Immunol. 1984 Oct 1;88(1):9-15. doi: 10.1016/0008-8749(84)90047-9.
A synthetic N-acetylmuramyl-L-alanyl-D-isoglutamine or muramyl dipeptide (MDP) and adjuvant-active analogs, but not lipopolysaccharide (LPS), exhibited the augmenting effect on the proliferative response of thymocytes to phytohemagglutinin (PHA). MDP also had a comitogenic effect on PHA-stimulated T lymphocytes. It was shown that the thymocyte-stimulating effect of MDP is not through the production of the monikines by MDP-stimulated macrophages and that MDP has a direct action on lymphocytes.
一种合成的N-乙酰胞壁酰-L-丙氨酰-D-异谷氨酰胺或胞壁酰二肽（MDP）及其具有佐剂活性的类似物，而非脂多糖（LPS），对胸腺细胞对植物血凝素（PHA）的增殖反应表现出增强作用。MDP对PHA刺激的T淋巴细胞也有协同致有丝分裂作用。结果表明，MDP的胸腺细胞刺激作用并非通过MDP刺激的巨噬细胞产生单核因子，且MDP对淋巴细胞有直接作用。
Zotero 插件