Morley J, Sanjar S
J Physiol. 1984 Aug;353:93-9. doi: 10.1113/jphysiol.1984.sp015324.
Transport of lead particles along the mucosal surface of the frog oesophagus has been measured by direct observation with the aid of video recording. Electrical stimulation of the vagus nerve increased the rate of particle transport. This acceleration was suppressed by atropine or by hexamethonium. Acetylcholine and other parasympathomimetic agents accelerated particle transport rate. Such acceleration was abolished by atropine. Nicotine increased the rate of particle transport and this effect was suppressed by hexamethonium or by atropine. Atropine did not significantly alter basal particle transport rate. Neither basal particle transport rate nor the response to vagal nerve stimulation were affected by eserine. Adrenaline, noradrenaline or isoprenaline did not affect basal particle transport rate. Adrenaline or noradrenaline were without effect on the increased particle transport rate due to electrical stimulation of the vagus.
借助视频记录直接观察,测量了铅颗粒沿蛙食管黏膜表面的运输情况。迷走神经的电刺激增加了颗粒运输速率。这种加速作用被阿托品或六甲铵抑制。乙酰胆碱和其他拟副交感神经药物加快了颗粒运输速率。这种加速作用被阿托品消除。尼古丁增加了颗粒运输速率,且这种作用被六甲铵或阿托品抑制。阿托品并未显著改变基础颗粒运输速率。毒扁豆碱对基础颗粒运输速率或对迷走神经刺激的反应均无影响。肾上腺素、去甲肾上腺素或异丙肾上腺素不影响基础颗粒运输速率。肾上腺素或去甲肾上腺素对因迷走神经电刺激而增加的颗粒运输速率没有作用。