富含脯氨酸多肽（PRP）对体液免疫反应的影响。I. PRP对去胸腺小鼠玻璃非黏附（NAT）和玻璃黏附（GAT）胸腺细胞T细胞特性的独特影响。
The effect of a proline-rich polypeptide (PRP) on the humoral immune response. I. Distinct effect of PRP on the T cell properties of mouse glass-nonadherent (NAT) and glass-adherent (GAT) thymocytes in thymectomized mice.
作者信息
Zimecki M, Lisowski J, Hrabă T, Wieczorek Z, Janusz M, Starościk K
出版信息
Arch Immunol Ther Exp (Warsz). 1984;32(2):191-6.
It has been shown, using thymectomized, irradiated and reconstituted mice and a proline-rich polypeptide (PRP) that glass-nonadherent thymocytes contain a precursor of helper cell, and glass-adherent thymocytes a precursor of suppressor cells in the humoral immune response to SRBC. Precursor cells differentiate into helper or suppressor cells upon in vitro contact with PRP. Moreover, it was demonstrated that NAT and GAT fractions are related to PNA+ and PNA- thymocytes respectively.
已经表明，利用经胸腺切除、辐照并重建的小鼠以及富含脯氨酸的多肽（PRP），在对SRBC的体液免疫反应中，玻璃非黏附性胸腺细胞含有辅助细胞的前体，而玻璃黏附性胸腺细胞含有抑制细胞的前体。前体细胞在体外与PRP接触后分化为辅助细胞或抑制细胞。此外，还证明了NAT和GAT组分分别与PNA+和PNA-胸腺细胞相关。
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