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[过去17年中波鸿市1322例住院患者的喉气管狭窄性炎症(假膜性喉炎)的流行病学及症状]

[Epidemiology and symptoms of stenosing laryngotracheitis (pseudo-croup) in 1322 inpatients in Bochum in the last 17 years].

作者信息

Mietens C, Lütkemeyer B, Köhler S

出版信息

Monatsschr Kinderheilkd. 1984 Sep;132(9):646-53.

PMID:6333586
Abstract

During the 17 years period from 1967 to 1983 a total number of 1322 children were hospitalized for infectious croup (stenosing laryngotracheitis) at the Children's Hospital in Bochum. The epidemiology of this disease, especially the yearly and seasonal incidence as well as clinical symptoms were analyzed. For this purpose at least 18 data were obtained from each patient and processed by computer using an especially elaborated FORTRAN IV program. The main incidence of infectious croup was in fall and winter, with a peak in September and October. The symptoms began usually at nighttime and boys were affected 2.5 times more frequently than girls. The risk of disease was highest in the second year of life and decreased sharply with the begin of school age. Sixteen per cent of the children had recurrent attacks of stenosing laryngotracheitis. The main therapeutic procedures were listed and discussed. Besides air humidification, sufficient application of liquids and steroids in serious cases, racemic epinephrine given by mask and positive pressure ventilation has been demonstrated to be very effective. While the viral etiology of this disease has been well established possibilities in which way meteorological and environmental factors might contribute to the manifestation of this disease are discussed. This problem can be solved only by prospective investigations. No statistically relevant increase in the number of cases of stenosing laryngotracheitis during recent years can be found in the presented results.

摘要

在1967年至1983年的17年间,共有1322名儿童因感染性喉炎(狭窄性喉气管炎)在波鸿儿童医院住院。对该疾病的流行病学,尤其是年发病率和季节发病率以及临床症状进行了分析。为此,从每位患者那里至少获取了18项数据,并使用一个特别编制的FORTRAN IV程序通过计算机进行处理。感染性喉炎的主要发病时间在秋季和冬季,9月和10月达到高峰。症状通常在夜间开始出现,男孩患病的频率是女孩的2.5倍。发病风险在儿童出生后的第二年最高,随着学龄期的开始而急剧下降。16%的儿童有狭窄性喉气管炎的复发发作。列出并讨论了主要的治疗方法。除了空气加湿、充足的液体摄入以及在严重病例中使用类固醇外,面罩给予消旋肾上腺素和正压通气已被证明非常有效。虽然该疾病的病毒病因已得到充分证实,但仍讨论了气象和环境因素可能以何种方式促成该疾病表现的可能性。这个问题只有通过前瞻性研究才能解决。在所呈现的结果中,未发现近年来狭窄性喉气管炎病例数有统计学上的显著增加。

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