作为药物制剂的N-三氟乙酰衍生物。III. 某些抗炎三氟乙酰苯胺的镇痛、解热活性及物理化学特性
N-trifluoroacetyl derivatives as pharmacological agents. III. Analgesic, antipyretic activities and physicochemical features of some antiinflammatory trifluoroacetanilides.
作者信息
Vigorita M G, Saporito G, Nastasi S, Costa De Pasquale R, Occhiuto F, Circosta C
出版信息
Farmaco Sci. 1984 Sep;39(9):810-6.
PMID:6333993
Abstract
Further pharmacological (antipyretic and analgesic activities) and physicochemical (pka and relative lipophilicity) studies are reported on some trifluoroacetanilides which have preliminary revealed promising activities in the animal models of acute and chronic inflammation, in analogy with the known antiinflammatory trifluoromethanesulfonanilides.
摘要
对一些三氟乙酰苯胺进行了进一步的药理（解热和镇痛活性）和物理化学（pKa和相对亲脂性）研究，这些研究初步显示，与已知的抗炎三氟甲磺酰苯胺类似，它们在急慢性炎症动物模型中具有有前景的活性。
Zotero 插件