与磺胺嘧啶银治疗相关的急性白细胞减少症。
Acute leukopenia associated with silver sulfadiazine therapy.
作者信息
Valente P, Axelrod J L
出版信息
J Trauma. 1978 Feb;18(2):146-7. doi: 10.1097/00005373-197802000-00016.
Abstract
A patient with a 30% scald burn was treated with topical silver sulfadiazine (Silvadene). On two occasions, within 48 hours of treatment, the patient developed acute leukopenia. Bone marrow aspiration revealed cell maturation arrest. The possible mechanisms of this leukopenia are discussed. It is recommended that daily leukocyte counts be done in burn patients being treated with silver sulfadiazine.
摘要
一名30%体表面积烫伤的患者接受了磺胺嘧啶银（烧伤宁）局部治疗。在治疗后的48小时内，患者出现了两次急性白细胞减少。骨髓穿刺显示细胞成熟停滞。本文讨论了这种白细胞减少的可能机制。建议对接受磺胺嘧啶银治疗的烧伤患者进行每日白细胞计数。
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