Poulter N, Khaw K T, Hopwood B E, Mugambi M, Peart W S, Rose G, Sever P S
Hypertension. 1984 Nov-Dec;6(6 Pt 1):810-3. doi: 10.1161/01.hyp.6.6.810.
Blood pressure (BP) and associated factors were determined in 1737 men in a remote Kenyan agricultural community. Systolic BP showed no significant rise with age until after 54 years; diastolic BP showed a small rise with age. Both systolic and diastolic BP correlated with weight independent of age. Systolic and diastolic BP correlated positively with casual urinary sodium/potassium and negatively with potassium/creatinine ratios. Both systolic and diastolic BP correlated significantly with the number of years of education, as did urinary sodium/potassium and sodium/creatinine ratios. Potassium/creatinine ratios were negatively correlated with the number of years of education. Blood pressure and urinary sodium/creatinine ratios were significantly lower in subsistence farmers compared with those in other occupations, and potassium/creatinine ratios were significantly higher. Two pilot studies of Luo tribesmen showed a strong correlation between casual urinary electrolyte ratios and those derived from 24-hour urine samples and a greater variance of sodium excretion between these people than that found within individuals. These results suggest that a relationship between BP and casual urine electrolyte estimations may be identifiable in communities where there is less day-to-day dietary variation. They also suggest that some of the changes in BP associated with urbanization could be mediated by changes in dietary electrolytes.
在肯尼亚一个偏远农业社区的1737名男性中测定了血压（BP）及相关因素。收缩压在54岁之前随年龄增长无显著升高；舒张压随年龄有小幅升高。收缩压和舒张压均与体重相关，且不受年龄影响。收缩压和舒张压与随意尿钠/钾呈正相关，与钾/肌酐比值呈负相关。收缩压和舒张压均与受教育年限显著相关，随意尿钠/钾和钠/肌酐比值也如此。钾/肌酐比值与受教育年限呈负相关。与其他职业者相比，自给自足农民的血压和尿钠/肌酐比值显著较低，而钾/肌酐比值显著较高。两项针对卢奥部落男子的初步研究表明，随意尿电解质比值与24小时尿样得出的比值之间有很强的相关性，且这些人之间的钠排泄差异比个体内差异更大。这些结果表明，在日常饮食变化较小的社区中，可能可以确定血压与随意尿电解质测定值之间的关系。它们还表明，与城市化相关的一些血压变化可能由饮食电解质的变化介导。
