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[仅通过经迷路入路进行的听神经大神经鞘瘤手术。附50例报告]

[Surgery of large neurinomas of the acoustic nerve performed only by the translabyrinthine approach. Apropos of 50 cases].

作者信息

Desgeorges M, Sterkers J M

出版信息

Neurochirurgie. 1984;30(6):355-64.

PMID:6335571
Abstract

A combined otoneurosurgical team has operated upon 68 patients with acoustic nerve neurinomas over a period of 13 months (Sept. 1982-Oct. 1983). Exploration and operation in this homogeneous series were carried out under the same conditions, and a CT scan was performed in each patient before and after surgery. The size of the neuroma was less than 2 cm in diameter in 18 cases, between 2 and 3 cm in 28 cases, between 3 and 4 cm in 10 and 4 cm or more in 12. This report relates to the 50 neurinomas over 2 cm in diameter, these requiring multidisciplinary co-operation during surgical removal. The translabyrinthine approach was used exclusively in 48 cases, and was combined with a retrosigmoid approach in the other 2 cases. Total tumoral excision was possible in 46 cases (92%) and partial removal in 4 patients (8%). Complications included one death (bilateral giant neurinomas), resolving purulent meningitis (2 cases), 3 patients with cerebrospinal fluid fistulae which healed after lumbar drainage, and 1 case of postoperative hematoma in the ponto-cerebellar angle requiring further surgery. The facial nerve was undamaged in 48 cases (96%). Postoperative facial palsy developed in 39 cases, and 15 have recovered subnormal motility. Follow up is insufficient in the other 17 patients. It is suggested that the translabyrinthine approach enables ablation of neurinomas of whatever size. This approach is reliable since it avoids injury to neighboring nerve structures. The facial nerve is detected immediately and can be protected throughout operation. The latter is, however, a long and difficult procedure, and otoneurosurgical collaboration is advisable.

摘要

一个耳神经外科联合团队在13个月(1982年9月至1983年10月)内为68例听神经鞘瘤患者进行了手术。在这个同质系列中,探查和手术均在相同条件下进行,并且每位患者在手术前后都进行了CT扫描。神经瘤直径小于2 cm的有18例,直径在2至3 cm之间的有28例,直径在3至4 cm之间的有10例,直径在4 cm及以上的有12例。本报告涉及直径超过2 cm的50例神经鞘瘤,这些肿瘤在手术切除过程中需要多学科合作。48例仅采用经迷路入路,另外2例采用经迷路入路联合乙状窦后入路。46例(92%)实现了肿瘤全切,4例(8%)为部分切除。并发症包括1例死亡(双侧巨大神经鞘瘤)、化脓性脑膜炎好转(2例)、3例脑脊液漏经腰大池引流后愈合,以及1例桥小脑角术后血肿需进一步手术。48例(96%)面神经未受损。39例出现术后面瘫,其中15例恢复至运动功能低于正常水平。另外17例患者随访不足。建议经迷路入路能够切除任何大小的神经鞘瘤。该入路可靠,因为它避免了对邻近神经结构的损伤。面神经能立即被识别,并且在整个手术过程中都能得到保护。然而,这是一个漫长且困难的手术过程,耳神经外科协作是可取的。

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European Association of Neurosurgical Societies, Seventh European lecture. Warsaw, March 1, 1986. Predictability of outcome in neurological surgery.
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