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抗α-淀粉酶的营养研究:I)对大鼠生长速率、血象、生化指标及组织学参数的影响。

Nutritional studies on anti alpha-amylase: I) Influence on the growth rate, blood picture and biochemistry and histological parameters in rats.

作者信息

Maranesi M, Carenini G, Gentili P

出版信息

Acta Vitaminol Enzymol. 1984;6(4):259-69.

PMID:6335947
Abstract

Anti-alpha-amylase is a protein characterized by an antienzymatic activity in the sense that it prevents hydrolysis of the alpha--1,4 glycoside bond of starch. Such action could be exploited for reducing the caloric value of the diet. We studied the in-vivo effectiveness of large doses of anti-alpha-amylase extracted from white beans (Phaseolus vulgaris). The growth rate of rats was clearly impaired, the blood pictures and biochemistry showed modifications, and the internal organ histology revealed alterations in the liver and kidney.

摘要

抗α-淀粉酶是一种具有抗酶活性的蛋白质,即它能阻止淀粉的α-1,4糖苷键水解。这种作用可用于降低饮食的热量值。我们研究了从白豆(菜豆)中提取的大剂量抗α-淀粉酶的体内有效性。大鼠的生长速度明显受损,血液检查和生化指标出现变化,内脏组织学显示肝脏和肾脏有改变。

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Nutritional studies on anti alpha-amylase: I) Influence on the growth rate, blood picture and biochemistry and histological parameters in rats.抗α-淀粉酶的营养研究:I)对大鼠生长速率、血象、生化指标及组织学参数的影响。
Acta Vitaminol Enzymol. 1984;6(4):259-69.
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引用本文的文献

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Common bean (Phaseolus vulgaris L.) α-amylase inhibitors as safe nutraceutical strategy against diabetes and obesity: An update review.普通菜豆(Phaseolus vulgaris L.)α-淀粉酶抑制剂作为防治糖尿病和肥胖的安全营养策略:最新综述。
Phytother Res. 2022 Jul;36(7):2803-2823. doi: 10.1002/ptr.7480. Epub 2022 Apr 29.
2
An in vitro and in vivo study of the α-amylase activity of phaseolamin.菜豆素α-淀粉酶活性的体外和体内研究
J Med Food. 2014 Aug;17(8):915-20. doi: 10.1089/jmf.2013.0044. Epub 2014 Mar 20.
3
A review on botanical species and chemical compounds with appetite suppressing properties for body weight control.
关于具有抑制食欲和控制体重特性的植物物种和化学成分的综述。
Plant Foods Hum Nutr. 2013 Sep;68(3):213-21. doi: 10.1007/s11130-013-0361-1.
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Potential efficacy of preparations derived from Phaseolus vulgaris in the control of appetite, energy intake, and carbohydrate metabolism.菜豆属植物制剂控制食欲、能量摄入和碳水化合物代谢的潜在功效。
Diabetes Metab Syndr Obes. 2009 Sep 7;2:145-53. doi: 10.2147/dmsott.s4236.
5
The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents.脂质和碳水化合物消化酶抑制剂在肥胖管理中的作用:当前和新兴治疗药物的综述。
Diabetes Metab Syndr Obes. 2010 May 10;3:125-43. doi: 10.2147/dmsott.s7005.