Shiokawa Y, Iida N, Taniguchi K
Jpn Circ J. 1978 Jan;42(1):39-42. doi: 10.1253/jcj.42.39.
Cellular immunity to non-specific antigens (PPD, Candida albicans, and streptococcal antigens) and mitogen (PHA) was investigated in patients with valvular heart disease of rheumatic origin. The result disclosed that lowered response in cellular immunity exists in these patients. The possible significance of this finding in occurrence of rheumatic activity was discussed.