Dévay A, Fekete P, Rácz I
Pharmaceutical Institute of Semmelweis Medical University, Budapest, Hungary.
J Microencapsul. 1984 Oct-Dec;1(4):299-305. doi: 10.3109/02652048409031542.
The authors studied the parameters of sustained released Tofizopam microcapsules, prepared by a melt-dispersion method. The parameters examined were the flowing rate, strength and dissolution characteristics. Dissolution curves were linearized by the RRSBW distribution. The factorial design method proved to be very useful for examination of microcapsules.
作者研究了采用熔融分散法制备的托非索泮缓释微胶囊的参数。所检测的参数包括流速、强度和溶解特性。通过RRSBW分布使溶解曲线线性化。析因设计方法被证明对微胶囊的检测非常有用。