Matsunaga M, Hara A, Song T S, Hashimoto M, Tamori S, Ogawa K, Morimoto K, Pak C H, Kawai C, Yoshida O
Hypertension. 1983 Mar-Apr;5(2):240-3. doi: 10.1161/01.hyp.5.2.240.
We report a case of primary aldosteronism in a 30-year-old woman without hypertension or any other characteristic symptoms. The condition was first suspected by hypokalemia (2.6 mEq/liter), which was incidentally found by routine checkup. There was evidence of suppressed plasma renin activity (PRA) and elevated plasma aldosterone levels. However, the blood pressure never reached a hypertensive level, and the circulating blood volume was within a normal range. A functioning right adrenal tumor was diagnosed by adrenal scintigraphy, computerized x-ray tomography, and adrenal venography. Adrenal venous catheterization suggested an aldosteronoma, which was confirmed by lateralized hypersecretion of aldosterone. After removal of the benign adenoma, the biochemical abnormalities were corrected, yet the blood pressure remained much the same. Hypertension is not necessarily a sign of primary aldosteronism.
我们报告一例30岁女性原发性醛固酮增多症病例，该患者无高血压或任何其他特征性症状。病情最初因低钾血症（2.6毫当量/升）而被怀疑，低钾血症是在常规体检时偶然发现的。有血浆肾素活性（PRA）受抑制和血浆醛固酮水平升高的证据。然而，血压从未达到高血压水平，循环血容量在正常范围内。通过肾上腺闪烁显像、计算机断层扫描和肾上腺静脉造影诊断为右侧肾上腺功能性肿瘤。肾上腺静脉插管提示醛固酮瘤，醛固酮侧支性分泌增多证实了这一诊断。切除良性腺瘤后，生化异常得到纠正，但血压仍大致相同。高血压不一定是原发性醛固酮增多症的体征。
