Rosichan J L, Owais W M, Kleinhofs A, Nilan R A
Mutat Res. 1983 Mar;119(3):281-5. doi: 10.1016/0165-7992(83)90173-2.
The ability of Arabidopsis, Drosophila and Neurospora to convert azide to its mutagenic metabolite was investigated. Cultures of these organisms all contained significant levels of O-acetylserine sulfhydrylase activity. Extracts from each organism produced a product from O-acetylserine and azide in vitro which was mutagenic in Salmonella typhimurium TA1530.
研究了拟南芥、果蝇和粗糙脉孢菌将叠氮化物转化为其诱变代谢物的能力。这些生物体的培养物均含有显著水平的O-乙酰丝氨酸巯基酶活性。每种生物体的提取物在体外由O-乙酰丝氨酸和叠氮化物产生一种产物，该产物在鼠伤寒沙门氏菌TA1530中具有致突变性。
