培养的植物细胞对2-氨基芴的激活作用。
Activation of 2-aminofluorene by cultured plant cells.
作者信息
Plewa M J, Weaver D L, Blair L C, Gentile J M
出版信息
Science. 1983 Mar 25;219(4591):1427-9. doi: 10.1126/science.6338591.
PMID:6338591
Abstract
Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2-aminofluorene is heat-inactivated and may not involve solely cytochrome P-450. The kinetics of activation demonstrated both time- and concentration-dependent responses.
摘要
培养的烟草植物细胞将2-氨基芴激活为对鼠伤寒沙门氏菌TA98菌株具有致突变性的物质。2-氨基芴的植物激活作用会被热灭活，且可能不仅仅涉及细胞色素P-450。激活动力学显示出时间和浓度依赖性反应。
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