吲哚洛尔对青光眼眼压的影响：初步研究及与噻吗洛尔的随机对照比较。
Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol.
作者信息
Andréasson S, Jensen K M
出版信息
Br J Ophthalmol. 1983 Apr;67(4):228-30. doi: 10.1136/bjo.67.4.228.
Abstract
A pilot study on 10 consecutive patients with newly diagnosed glaucoma and a randomised double-blind study on 18 patients with glaucoma were carried out to investigate the effect of pindolol, a beta-adrenergic blocking agent, on the intraocular pressure (IOP) in patients with glaucoma. The studies showed that pindolol may reduce the IOP and that no significant difference between the effect of timolol 0.5% and of pindolol 0.25% could be demonstrated. The serum concentration of pindolol was measured in 9 of the patients, but none had measurable serum levels.
摘要
对10例新诊断的青光眼患者进行了一项初步研究，并对18例青光眼患者进行了一项随机双盲研究，以调查β-肾上腺素能阻滞剂吲哚洛尔对青光眼患者眼压（IOP）的影响。研究表明，吲哚洛尔可能降低眼压，且未发现0.5%噻吗洛尔与0.25%吲哚洛尔的效果之间存在显著差异。对9例患者测量了吲哚洛尔的血清浓度，但均未检测到可测量的血清水平。
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Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol.吲哚洛尔对青光眼眼压的影响：初步研究及与噻吗洛尔的随机对照比较。
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