一种参与大肠杆菌中由DNA聚合酶I形成DNA合成复合物的细胞因子。
A cellular factor involved in the formation of a DNA-synthesizing complex from DNA polymerase I in Escherichia coli.
作者信息
Scharff R, Hanson M A, Hendler R W
出版信息
Biochim Biophys Acta. 1983 Apr 15;739(3):265-75. doi: 10.1016/0167-4781(83)90100-8.
PMID:6338927
Abstract
A factor ('E') has been identified which stabilizes an endogenous DNA-synthesizing complex involving DNA polymerase I. The complex is separated from free DNA polymerase by polyacrylamide gel electrophoresis. The factor will reform the complex after it has been dissociated and will convert a preparation of DNA polymerase I to complex. The factor and the DNA-synthesizing complex both appear to be localized at the cell membrane.
摘要
已鉴定出一种因子（“E”），它能稳定一种涉及DNA聚合酶I的内源性DNA合成复合物。该复合物通过聚丙烯酰胺凝胶电泳与游离的DNA聚合酶分离。该因子在解离后会重新形成复合物，并能将DNA聚合酶I制剂转化为复合物。该因子和DNA合成复合物似乎都定位于细胞膜。
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