Ivanov N R, Shenkman B Z
Biull Eksp Biol Med. 1983 Jan;95(1):32-5.
The salicylate content in blood plasma after its administration into the stomach and small intestine during experimental endotoxemia in mice has been measured. In early stages of intoxication gastric evacuation was fairly slow. Histamine increased, while its antagonist pyrilamine significantly reduced the observed disorder. In the last stages of intoxication, passive absorption in the small intestine increased. Administration of histamine, serotonin and ciproheptadine did not produce any essential effect on the salicylate transport across the intestinal wall.
对实验性内毒素血症小鼠经胃和小肠给药后血浆中的水杨酸盐含量进行了测定。在中毒早期，胃排空相当缓慢。组胺增加，而其拮抗剂吡苄明显著减轻了观察到的紊乱。在中毒后期，小肠的被动吸收增加。给予组胺、5-羟色胺和赛庚啶对水杨酸盐跨肠壁转运未产生任何显著影响。
