Schifter S, Vendelbo L, Jensen O M, Kaae S
Cancer. 1983 May 1;51(9):1746-9. doi: 10.1002/1097-0142(19830501)51:9<1746::aid-cncr2820510930>3.0.co;2-g.
Retinoblastoma is found in a hereditary and nonhereditary form. Long survivors treated for the hereditary form seem to be predisposed for developing a second primary tumor later in life. The retinoblastoma genes are supposed to be responsible for this disposition. This report describes the development of a Ewing's tumor in a nine-year-old girl, who had both eyes removed in early life for retinoblastoma.
视网膜母细胞瘤有遗传性和非遗传性两种形式。接受过遗传性视网膜母细胞瘤治疗的长期存活者似乎在晚年易患第二种原发性肿瘤。视网膜母细胞瘤基因被认为对此易感性负责。本报告描述了一名9岁女孩发生尤因肉瘤的情况,该女孩早年因视网膜母细胞瘤而摘除了双眼。