Gross A E, McKee N H, Pritzker K P, Langer F
Clin Orthop Relat Res. 1983 Apr(174):96-106.
From 1971 to 1982, 110 osteochondral transplants with follow-up evaluation were performed for treatment of skeletal deficits caused by degenerative, traumatic, and neoplastic diseases largely involving the knee joint. Seventy-eight small-fragment fresh allografts were transplanted for repair of old tibial plateau osteochondral fractures, osteonecrosis, and unicompartmental osteoarthritis. Thirty-two large-fragment grafts were performed following en bloc excision of bone tumors. Of these, 22 were allografts, three were vascularized fibular autografts, and seven were a combination of allografts and vascularized fibular autografts. In this large-fragment group, three grafts have been removed for tumor recurrence, two for infection, and one for a stress fracture. The results of these transplants have proved particularly rewarding in the old plateau fractures, for traumatic loss of bone and cartilage (osteonecrosis), and after en bloc excision of giant cell tumors.
1971年至1982年期间，共进行了110例骨软骨移植手术，并进行了随访评估，以治疗主要累及膝关节的退行性、创伤性和肿瘤性疾病引起的骨骼缺损。78例小碎片新鲜同种异体移植物被用于修复陈旧性胫骨平台骨软骨骨折、骨坏死和单髁骨关节炎。32例大碎片移植物是在整块切除骨肿瘤后进行的。其中，22例为同种异体移植物，3例为带血管腓骨自体移植物，7例为同种异体移植物与带血管腓骨自体移植物的联合应用。在这个大碎片移植组中，有3例移植物因肿瘤复发被移除，2例因感染被移除，1例因应力性骨折被移除。这些移植手术的结果在陈旧性平台骨折、创伤性骨与软骨丢失（骨坏死）以及整块切除巨细胞瘤后尤其令人满意。
